Primary Care in Rochester and Kasson

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Find a Study

Your team in Primary Care strongly supports research. Our staff members participate in research studies and often lead that research. Do consider participating.

The following listing(s) are for research conducted by Mayo Clinic and the listing(s) are intended for your consideration as a member of our community.

Visit the Clinical Trials at Mayo Clinic website to find trials that you might join. Clinical trials are studies where patients with certain conditions are allocated to different treatments by random (as in the flip of a coin). To learn more about the Clinical Trial Journey view this short video, it is available in both English and Spanish

In addition, we will post additional studies below when the investigator has requested that the study be advertised directly to our community. 

  • Recruiting healthy teenagers for a brain scan study

    Mayo Clinic is seeking eligible volunteers for a research study. You may be eligible to participate if: 

    • You are 12-18 years of age
    • You have never had treatment of depression or other psychiatric disorders

    The purpose of this study is to examine the brain function of healthy adolescents and adolescents with depression. 

    Participants will come to Mayo Clinic for a screening visit (approximately two hours) and then travel to the University of Minnesota, Minneapolis, Minn., for two magnetic resonance imaging (MRI) scans (this visit takes approximately 4 hours and will be scheduled on a Friday). 

    Participants are reimbursed for their time and travel to Minneapolis. 

    For more information, contact Paul Croarkin, DO (507-283-2557), Marjorie Gresbrink (507-255-0624), or Jeremy Weiss (507-255-0001). 

  • Fiber and Diabetes (FAD) Study: Effect of Psyllium vs. Wheat Dextrin on Glycemic Control and Inflammatory Markers in Diabetes Mellitus 2

    Mayo Clinic is seeking adult volunteers with Type 2 diabetes to participate in a research study. The purpose of this study is to research which type of over-the-counter fiber supplement, such as Metamucil™ (psyllium) or Benefiber™ (wheat dextrin), has a greater effect on lowering fasting glucose, cholesterol and certain inflammatory markers in the blood. 

    You may be eligible to participate if:

    • You receive care through Mayo Clinic Primary Care in Rochester 
    • You have Type 2 diabetes

    This study may not make your health better; however, your lab values may be maintained or improved. 

    • As with any medication, allergic reactions are possible. 
    • If you think you might be pregnant during the study, you must tell the Principal Investigator immediately. If a pregnancy is confirmed, you would no longer be eligible to participate in the study. 
    • The risks of drawing blood include pain, bruising, lightheadedness, and/or fainting, or rarely, infection at the site of the needle stick. 
    • As with all research, there is a chance that confidentiality could be compromised; however, we take precautions to minimize this risk. 

    Estimated time or other commitment required of the subject: Approximately 12 weeks. 

    You will receive $20 for each in-person study visit you complete (up to $80 total for all visits). You will also receive a parking voucher worth up to $6 for each in-person visit (up to $24 total). 

    For more information about this study, please contact the Family Medicine Research Study Coordinators via email (RSTFMSC@mayo.edu) or telephone (507-422-6823). 

  • GUARD-AF: reducinG stroke by screening for UndiAgnosed atRial fibrillation in elderly inDividuals

    Mayo clinic is seeking volunteers to participate in a research study to determine if using a device to detect previously unknown or undiagnosed atrial fibrillation or atrial flutter (heart rhythm abnormalities) reduces the risk of future stroke compared to usual care. 

    You may be eligible to participate if: 

    • You are age 70 or older.
    • You are a Mayo Clinic patient in Southeast Minnesota or Western Wisconsin.
    • You are willing to allow the use of your personal health information (including Medicare Beneficiary Identifier) to find out if any events related to atrial fibrillation or atrial flutter occurred during the study period. 
    • You have the ability to apply and wear the heart monitor by yourself, or with caregiver help.
    • And you do not:
      • Have Medicare Advantage health insurance (Part C)
      • Take oral blood thinners
      • Have a history of atrial fibrillation or atrial flutter. 
      • Have severe kidney impairment. 
      • Have any implanted cardiac devices. 
      • Have an allergy to adhesives. 

    You may not have direct benefit from taking part in this study; however, if you are assigned to wear the device and are found to have atrial fibrillation (AF) or atrial flutter (AFL), proper follow-up may help reduce the risk of stroke for you or other patients who were not previously aware they had AF or AFL. 

    The known risks associated with this study are minimal. One possible risk is a skin rash or skin irritation from the adhesive that holds the ZIO® XT Patch. If this occurs, you can remove the patch and you should contact your primary care provider. Another possible risk is finding you have AF or AFL, which could lead your provider to prescribe a blood thinner, which can cause bleeding. As with all research, there is a chance that confidentiality could be compromised; however, we take precautions to minimize this risk. 

    Estimated time or other commitment required for the study:

    • Approximately 20 minutes for prescreening questions by phone. 
    • Approximately 45-60 minutes for enrollment visit either in person or remotely (mail or email along with a phone discussion). 

    Compensation will be provided for time spent in the study. 

    For more information contact your region's Family Medicine Study Coordinator:

  • Randomized Controlled Trial of Stress Management and Resiliency Training for Depression (SMART-D) vs. Treatment as Usual in the Treatment of Major Depression

    Mayo Clinic is seeking participants in a study to see whether a modified SMART therapy program can help patients with depression, compared to their treatment as usual. Participants would have a 50/50 chance of being in either an 8-week SMART-D program that would consist of 6 virtual group sessions with a study provider, or will continue their treatment as usual. Participants will complete questionnaires throughout the study for up to 6 months after starting the SMART program. 

    To be considered for this study:

    • Study subjects must be a current patient in one of the following areas:
      • Mayo Clinic Depression Center
      • Mayo Clinic Family Medicine primary care in the following locations
        • Rochester - Baldwin clinic, Mayo Family Clinic Northeast, Mayo Family Clinic Northwest, Mayo Family Clinic Southeast
        • Kasson - Mayo Family Clinic Kasson
        • Mayo Clinic Health System in Austin
        • Mayo Clinic Health System in Albert Lea
      • Integrated Behavioral Health
    • Be between 25 and 80 years of age
    • Must be able to speak English
    • Provide written informed consent to participate in the study
    • Have a DSM-V diagnostic confirmation of major depressive disorder (MDD) (American Psychiatric Association 2013) - participants with a co-morbid secondary diagnosis of persistent depressive disorder and generalized anxiety disorders will be included
    • Continue taking prescribed medications from the clinical treatment team
    • Consent to audio recording of random group sessions (these will be disclosed at the final study session)
    • Have a current Patient Online Services account (or agree to sign up for the account) for all communication purposes during the study

    The following are exclusion criteria for the study:

    • Pregnant women (due to time duration of the study)
    • Diagnosis of a severe major depressive episode (HAM-D scores > 19)
    • Bipolar disorders, active psychosis, active suicidal ideation, and active substance abuse meeting criteria for substance abuse disorder (except nicotine), obsessive-compulsive disorder, active panic disorder with agoraphobia or other phobic disorder, active post-traumatic stress disorder, active severe personality disorder

    While this study may not make your health better, the SMART-D therapy may help to improve your mood. 

    Estimated time or other commitment required: 6 months

    Compensation will be offered for completing the outcome measures at each follow-up point in the study (e.g., Week 1, Week 8, 3-month post-SMART-D, and 6-month post-SMART-D visits). 

    For more information about the study, contact Laura Harper via email (harper.laura1@mayo.edu or telephone (507-255-9352). 

  • Do you have a teen with depression?

    Mayo Clinic is seeking eligible volunteers for a research study. Your adolescent may be eligible to participate if: 

    • They are between the ages of 12 and 18
    • They have been diagnosed with a major depressive disorder
    • They have been depressed for at least the last four weeks

    The purpose of this study is to see if transcranial magnetic stimulation therapy can be used to treat depression in adolescents. (This therapy is currently approved by the FDA to treat adults with depression.)

    Study participants will come every weekday for six weeks (total of 30 treatments). Each treatment session is one hour in length and you and your adolescent will be asked to complete an assessment each week. 

    Participants will be reimbursed for their time and parking. 

    For more information, contact Marjorie Gresbrink (507-255-0624) or Jeremy Weiss (507-255-0001). 

  • Efficacy of Intralesional Vitamin D Injection for Treatment of Common Warts: A Randomized Controlled Trial

    Mayo Clinic is seeking adult volunteers with one or more cutaneous warts (common, plantar, and flat warts), to participate in a research study. The purpose of this study is to explore the effectiveness of Vitamin D injection as a treatment for common warts by comparing subjects whose warts have been injected with Vitamin D versus placebo. 

    You may be eligible to participate if:

    • You are an adult patient (age 18 or older)
    • Are seen at one of the Mayo Rochester primary care clinics
    • Have a wart (common, plantar, or flat) that you would like treated

    Risks of being included:

    • Some pain, discomfort, or bleeding at the injection site
    • Low risk of infection, scarring, redness or discoloration of the skin
    • Swelling or itching at the injection site
    • No improvement of the wart

    Participation will last up to six months and may include up to five study visits. Participants will receive up to three injections of the study medication into the wart of their choice. Visits will include photographs and measurements of the wart, medication review, and questionnaires. Surveys will be emailed one week after each injection. 

    Participants will be compensated for time spent in the study. 

    For more information, contact the Family Medicine study coordinators at RSTFMSC@mayo.edu